Pancreatitis Causes

Most cases of acute pancreatitis are closely related to gallstones and alcohol consumption, although the exact cause is not always clear.

Pancreatitis occurs when digestive enzymes produced in the pancreas of patients to be active when they are inside the pancreas. This causes damage to the pancreas. During normal digestion in healthy individuals, inactivated enzyme produced in the pancreas to move through the pancreatic duct.

What could be causing chronic pancreatitis?

Body can produce gall bladder stones as poor eating patterns, body acids, hormonal changes, lack of regular exercise, or overweight and being obese. Gallstone size can range upwards from a piece of sand size. Uncontrolled alcohol consumption also leads to chronic pancreatitis. Regardless of these factors, pancreatitis can occur because of damage or injury that occurs in the pancreas. The accident also interferes with the function of this gland.

Acute Pancreatitis

The exact cause of acute pancreatitis is unclear, but most experts think that it has to do with a chemical called trypsin. Trypsin is an enzyme produced by the pancreas. It is used to help break down proteins in food to aid digestion.

When trypsin is produced by the pancreas remains in a state of ‘inactive’ and do not have digestive properties. It is not until it is removed from the pancreas and into the intestines can become active and begins to break down proteins.

It is estimated that something causes trypsin to become active while still in the pancreas and that it may begin to break down cells of the pancreas. As a result, begin to digest the pancreas itself, causing it to become irritated and inflamed.

Other causes

Common cause of acute pancreatitis

Accidental damage to the pancreas that occurs during this type of surgery known as endoscopic retrograde cholangiopancreatography (ERCP), which is used to remove gallstones or check the pancreas or surrounding tissue

Certain types of medications, such as some antibiotics or chemotherapy drugs – Acute pancreatitis can be a side effect that is unexpected in a small number of people

Viral infections such as measles and smallpox

Consumption of alcohol

It is not fully understood how alcohol causes inflamed pancreas. One explanation is the ethanol in the alcohol molecules affects the normal working of pancreatic cells, getting them to activate trypsin prematurely.

Cause, there is a clear connection between alcohol use and acute pancreatitis, and a lot of alcohol that you consume or you drink, the higher your risk.

Some studies have found that people who regularly drink more than 35 units of alcohol a week were four times more likely to develop acute pancreatitis than those who did not drink alcohol (equivalent to 35 units of about 16 cans of drink strong beer or four bottles of wine a week).

someone who is drinking or consuming a lot of alcohol in a short time, it is believed to be able to increase the risk of developing acute pancreatitis.

Gallstone

Gallstones are hard pieces of material such as stones can form when your bile (digestive juices) have too much cholesterol in it. Sometimes gallstones can move out of the gallbladder and block the gap (channel) of the pancreas.

It is estimated that the blockage causes interference in the chemical reactions that occur in the pancreas. This could lead to activation of trypsin in the pancreas and trigger the inflammation process.

Severe pancreatitis

Little is known about why some people develop severe acute pancreatitis. Factors thought to increase the risk include:

Be 70 years or more

Obesity – a person is considered obese if they have a body mass index (BMI) of 30 or above
had two or more alcoholic drinks a day

Cigarette

The researchers also found that people with a particular genetic mutation, known as MCP-1 mutation, eight times more likely to develop severe acute pancreatitis than the general population. A genetic mutation in which instructions (DNA) is found in all living cells become scrambled, resulting in genetic abnormalities or changes in characteristics.